Bloomipedia
Twinleaf (Jeffersonia diphylla)
Photo: Clay Gibbons via iNaturalist · CC BY 4.0 · resized

Flower profile

Twinleaf

Jeffersonia diphylla

Native in the lower 48

Twinleaf is a wildflower that USDA PLANTS lists as native in the lower 48 states. It's on our flower lists for 2 states, and across the U.S. it's most often seen in bloom in March–April.

18states
2of our state lists
6,268U.S. sightings*

*iNaturalist research-grade observations, as of October 17, 2026.

On our lists for: Kentucky, West Virginia

Quick look

Jeffersonia, also known as twinleaf or rheumatism root, is a small genus of herbaceous perennial plants in the family Berberidaceae. They are uncommon spring wildflowers and grow in limestone soils of rich deciduous forests. Jeffersonia was named for United States President Thomas Jefferson by his contemporary Benjamin Smith Barton. This genus was formerly grouped in genus Podophyllum.

  • It belongs to the Berberidaceae family. iNaturalist
  • USDA PLANTS describes it as an herb (forb) with a perennial life cycle. USDA PLANTS
  • USDA PLANTS lists it as native in the lower 48 states and records it in 18 states. USDA PLANTS
  • NatureServe lists it as native to Kentucky and West Virginia. NatureServe
  • In Kentucky, most iNaturalist sightings of it in flower come in March–April. iNaturalist
  • In West Virginia, most iNaturalist sightings of it in flower come in March–April. iNaturalist
  • iNaturalist has 933 research-grade sightings of it in Kentucky, ranking #64 among the 110 flowers on our Kentucky list. iNaturalist
  • iNaturalist has 411 research-grade sightings of it in West Virginia, ranking #87 among the 110 flowers on our West Virginia list. iNaturalist

Twinleaf gift ideas

Handmade twinleaf gifts from independent makers.

When does it bloom?

Flowering records by month across the U.S. (iNaturalist research-grade observations marked “Flowering”) (730 records)
Bloom time in each of our 2 states
StateTypePeak bloomSightings*
KentuckyNativeMarch–April933
West VirginiaNativeMarch–April411

Conservation status

Federal (U.S. ESA)
Not listed No U.S. Endangered Species Act listing in the USFWS ECOS database. USFWS ECOS
NatureServe global
G5 Secure worldwide. NatureServe
Kentucky
Not listed Not on Kentucky endangered and threatened plant lists (400 KAR 3:040, eff. 2026). NatureServe: S5, secure in Kentucky. 400 KAR 3:040
West Virginia
No list West Virginia has no state law listing endangered or threatened plants (only federally listed species are protected), so we show NatureServe's West Virginia ranks instead. NatureServe: S5, secure in West Virginia.
Rare elsewhere
Other states where NatureServe ranks it rare or missing: AL (S2), GA (S1), IA (S1), NC (S1), NJ (S1), NY (S2), WI (S2). (S1 critically imperiled, S2 imperiled, SH possibly extirpated, SX presumed extirpated.)

Checked October 17, 2026. Rankings and lists can change, so follow the links for the latest.

Can you eat it?

For peopleNot well documented

None of the sources we checked (NC State Extension (no edibility or poison notes on its page), USDA PLANTS) say whether it's edible or poisonous for people. NC State Extension

For petsNot well documented

It isn't on the ASPCA plant list, and NC State Extension doesn't flag it for pets.

🌿 Never eat a wild plant unless you're certain of its ID; this isn't medical advice. Worried about a person? Call Poison Control at 1-800-222-1222. Worried about a pet? Call your vet.

Where does it grow?

USDA PLANTS records twinleaf in 18 states plus Washington, D.C.

recorded by USDA PLANTS on our state lists not recorded

See the full list of states

Alabama, Georgia, Illinois, Indiana, Iowa, Kentucky, Maryland, Michigan, Minnesota, New Jersey, New York, North Carolina, Ohio, Pennsylvania, Tennessee, Virginia, West Virginia, Wisconsin; District of Columbia.

Kentucky counties with USDA records: Adair, Allen, Anderson, Bath, Boone, Boyle, Bracken, Breckinridge, Bullitt, Caldwell, Campbell, Carroll, Carter, Casey, Clark, Clay, Edmonson, Estill, Fayette, Franklin, Garrard, Grant, Green, Hardin, Hart, Henry, Jackson, Jefferson, Jessamine, Kenton, Laurel, Leslie, Lewis, Madison, Marion, Mason, McCreary, Meade, Menifee, Mercer, Metcalfe, Morgan, Nelson, Nicholas, Oldham, Owen, Pulaski, Rockcastle, Rowan, Trimble, Washington, Wayne, Woodford.

West Virginia counties with USDA records: Berkeley, Boone, Brooke, Cabell, Calhoun, Fayette, Gilmer, Grant, Greenbrier, Hampshire, Hardy, Harrison, Jefferson, Kanawha, Lincoln, Marion, Mason, Mercer, Monongalia, Nicholas, Ohio, Pendleton, Pleasants, Pocahontas, Raleigh, Ritchie, Roane, Summers, Tyler, Wayne, Wetzel, Wirt, Wyoming.

More Kentucky flowers

Sources